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| Section | Weight | Objectives |
|---|---|---|
| Topic 1: System-Based Standards and Population-Based Pharmacotherapy | 20% | - Population Health and Public Health
|
| Topic 2: Patient-Centered Pharmacotherapy | 55% | - Monitoring and Follow-Up
|
| Topic 3: Drug Information and Evidence-Based Medicine | 25% | - Literature Evaluation
|
1. A postmenopausal patient with osteoporosis is being switched from conjugated estrogen to raloxifene treatment. Which of the following should be communicated to this patient as the best outcome that has been documented with raloxifene?
A) Lower likelihood of thromboembolic events
B) Decreased incidence of Vertebral fractures
C) Decreased incidence of hot flushes
D) Decreased incidence of cardiovascular events
2. A 50-kg 15-year-old female patient presents to the emergency department 6 hours after ingesting 100 ferrous sulfate tablets, each containing 325 mg. A pregnancy test is negative, and flat plate radiography of the abdomen demonstrates many tablets in the stomach and throughout the small intestine. The patient is intermittently vomiting, with no tablets recovered in the emesis. The patient is otherwise asymptomatic and stable. Which of the following forms of gastrointestinal decontamination should be recommended?
A) Gastric lavage
B) Whole bowel irrigation
C) Ipecac syrup administration
D) Activated charcoal administration
3. A new team has been established in a large healthcare system to conduct research. At the first meeting of the new team, the pharmacotherapy specialist was asked to submit a proposal for a randomized clinical study. What is the first step in formulating the research hypothesis for this proposal?
A) Selecting an appropriate comparator
B) Formulating an answerable question
C) Determining a measurable outcome
D) Selecting a viable intervention
4. A study compared treatment with cinacalcet versus treatment with placebo in subjects with known hyperparathyroidism. The primary outcome of the study was the proportion of study subjects with a mean intact parathyroid hormone level < 250 pg/mL. Among the cinacalcet group (n = 371), 43% of subjects achieved the primary outcome; among the placebo group (n =
370), 5% achieved the primary outcome (p<0.05).
Which of the following is the number needed to treat (NNT)?
A) 3
B) 14
C) 1
D) 8
5. A 25-year-old woman who is HIV-positive and has a CD4+ count of 120 cells/mm begins antiretroviral therapy. The patient's CD4+ count drops to 45 cells/mm3 over the next year. For which of the following opportunistic infections should this patient receive prophylaxis?
A) Mycobacterium tuberculosis and CMV
B) MAC and Candida
C) MAC and Pneumocystis jirovecii pneumonia
D) Mycobacterium tuberculosis and Pneumocystis Jirovecii pneumonia
Solutions:
| Question # 1 Answer: C | Question # 2 Answer: B | Question # 3 Answer: B | Question # 4 Answer: A | Question # 5 Answer: C |
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